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Emmanuel Mignot Selected Research

Modafinil (Provigil)

4/2012Time-course of cerebrospinal fluid histamine in the wake-consolidated squirrel monkey.
11/2010Clinical and therapeutic aspects of childhood narcolepsy-cataplexy: a retrospective study of 51 children.
7/2006The neurobiology of hypocretins (orexins), narcolepsy and related therapeutic interventions.

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Emmanuel Mignot Research Topics

Disease

113Narcolepsy
07/2023 - 02/2000
55Cataplexy
01/2024 - 02/2000
26Disorders of Excessive Somnolence (Hypersomnia)
12/2023 - 10/2002
22Sleep Wake Disorders
01/2022 - 01/2002
11Sleepiness
07/2023 - 05/2003
11Sleep Apnea Syndromes (Sleep Apnea)
07/2022 - 12/2004
9Sleep Deprivation
07/2022 - 01/2004
7Sleep Initiation and Maintenance Disorders (Insomnia)
01/2022 - 10/2002
7Human Influenza (Influenza)
10/2020 - 10/2013
5Inflammation (Inflammations)
01/2022 - 08/2006
5Idiopathic Hypersomnia
01/2022 - 01/2007
4Infections
10/2023 - 12/2011
4Parkinson Disease (Parkinson's Disease)
01/2023 - 10/2002
4Obstructive Sleep Apnea
07/2022 - 10/2002
4Apnea
07/2022 - 11/2017
4Insulin Resistance
01/2011 - 08/2007
3Kleine-Levin Syndrome (Syndrome, Kleine-Levin)
12/2023 - 08/2015
3Cerebellar Ataxia (Dysmetria)
10/2023 - 01/2018
3Dementia (Dementias)
10/2023 - 01/2004
3Glioma (Gliomas)
01/2022 - 01/2021
3Autoimmune Diseases (Autoimmune Disease)
07/2020 - 06/2013
3Hypertension (High Blood Pressure)
11/2017 - 12/2004
3Nervous System Diseases (Neurological Disorders)
10/2010 - 10/2002
2Leukocytosis (Pleocytosis)
05/2024 - 10/2021
2Encephalitis (Encephalitis, Rasmussen)
10/2023 - 01/2022
2Restless Legs Syndrome (Restless Legs)
08/2023 - 10/2002
2Alzheimer Disease (Alzheimer's Disease)
01/2023 - 08/2017
2Limbic Encephalitis (Paraneoplastic Limbic Encephalitis)
10/2021 - 01/2021
2Genetic Predisposition to Disease (Genetic Predisposition)
07/2020 - 01/2004
2Schizophrenia (Dementia Praecox)
10/2019 - 05/2002
2Disease Susceptibility (Diathesis)
01/2015 - 02/2006
2Obesity
02/2013 - 12/2004
2Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2011 - 11/2009
2Multiple Sclerosis
03/2007 - 01/2004
2Type C Niemann-Pick Disease (Niemann Pick Disease, Type C)
06/2003 - 10/2002
1Autoimmune Diseases of the Nervous System
05/2024
1Synucleinopathies
02/2024
1Optic Atrophy
10/2023
1Psychotic Disorders (Schizoaffective Disorder)
10/2023
1Deafness (Deaf Mutism)
10/2023
1Chemical and Drug Induced Liver Injury
07/2023
1REM Sleep Behavior Disorder
01/2023

Drug/Important Bio-Agent (IBA)

93OrexinsIBA
01/2024 - 01/2002
22HLA-DQB1 antigen (HLA DQB1)IBA
01/2022 - 10/2002
12HLA Antigens (Human Leukocyte Antigens)IBA
01/2023 - 01/2007
11NeuropeptidesIBA
07/2023 - 11/2002
10AntibodiesIBA
05/2024 - 08/2009
10Sodium Oxybate (gamma Hydroxybutyrate)FDA Link
01/2023 - 11/2004
10Proteins (Proteins, Gene)FDA Link
01/2022 - 01/2011
8Biomarkers (Surrogate Marker)IBA
08/2023 - 01/2003
5AutoantibodiesIBA
10/2023 - 01/2009
5Orexin ReceptorsIBA
07/2023 - 06/2004
5Influenza Vaccines (Influenza Vaccine)FDA Link
01/2023 - 12/2013
5pandemrixIBA
01/2023 - 10/2013
5VaccinesIBA
10/2020 - 10/2013
5Antidepressive Agents (Antidepressants)IBA
04/2016 - 02/2000
5Neurotransmitter Agents (Neurotransmitter)IBA
06/2005 - 01/2002
4HLA-DQ Antigens (HLA-DQ)IBA
01/2015 - 10/2002
4Histamine (Histamine Dihydrochloride)FDA Link
12/2013 - 11/2002
4T-Cell Antigen Receptors (T-Cell Receptor)IBA
10/2013 - 06/2009
4HLA-DRB1 Chains (HLA DRB1)IBA
11/2008 - 01/2004
3Leucine (L-Leucine)FDA Link
01/2022 - 01/2021
3AntigensIBA
09/2021 - 03/2007
3Oxygen (Dioxygen)IBA
01/2021 - 11/2017
3arepanrixIBA
10/2020 - 07/2015
3C-Reactive ProteinIBA
11/2015 - 08/2006
3HLA-DQA1 antigen (HLA DQA1)IBA
01/2015 - 12/2013
3Cathepsin HIBA
10/2013 - 01/2013
3Purinergic Receptors (Receptors, Purine)IBA
10/2013 - 01/2011
3HDL CholesterolIBA
02/2013 - 08/2007
3Modafinil (Provigil)FDA Link
04/2012 - 07/2006
3Insulin (Novolin)FDA Link
01/2011 - 11/2009
3streptolysin OIBA
09/2010 - 08/2009
3LigandsIBA
08/2008 - 06/2004
3LeptinIBA
10/2007 - 01/2003
2gamma-Aminobutyric Acid (GABA)IBA
05/2024 - 11/2002
2EnzymesIBA
07/2023 - 01/2011
2SolutionsIBA
01/2022 - 01/2018
2Ataxin-3IBA
01/2022 - 08/2008
2Hemagglutinins (Hemagglutinin)IBA
10/2020 - 01/2019
2MethyltransferasesIBA
01/2020 - 10/2013
2DNA (Deoxyribonucleic Acid)IBA
01/2020 - 10/2013
2Peptides (Polypeptides)IBA
01/2019 - 12/2011
2Hypnotics and Sedatives (Sedatives)IBA
04/2016 - 07/2006
2CytokinesIBA
10/2015 - 08/2015
2EpitopesIBA
07/2014 - 12/2013
2Apolipoproteins E (ApoE)IBA
06/2013 - 02/2006
2ApolipoproteinsIBA
06/2013 - 02/2006
2Intravenous Immunoglobulins (IVIG)FDA Link
07/2012 - 10/2008
2deoxyribonuclease BIBA
09/2010 - 08/2009
2Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
04/2007 - 12/2004
2Amphetamine (Amfetamine)FDA LinkGeneric
07/2006 - 06/2005
2Dopamine (Intropin)FDA LinkGeneric
06/2004 - 11/2002
1N-(4-aminophenethyl)spiroperidol (NAPS)IBA
02/2024
1ramelteon (Rozerem)FDA Link
12/2023
1Melatonin Receptors (Melatonin Receptor)IBA
12/2023
1Proto-Oncogene Proteins c-sis (Platelet Derived Growth Factor B)IBA
10/2023
1Blood Proteins (Serum Proteins)IBA
08/2023

Therapy/Procedure

7Therapeutics
01/2023 - 07/2004
2Immunotherapy
05/2024 - 10/2021